Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
Purpose
The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.
Condition
- Colorectal Cancer Metastatic
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Age ≥ 18 - Non-amenable to curative hepatic resection as defined by FLR <30% - Histologically confirmed adenocarcinoma of the colon or rectum - Candidate for LDLT for colorectal liver metastasis per the University of Rochester liver transplant program
Exclusion Criteria
- Not a candidate of the LDLT liver transplant protocol for treatment of colorectal liver metastasis. - Unwilling to consent
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
| All Participants | Potential subjects for this registry must have Stage IV colorectal cancer with liver metastases and be candidates for liver transplantation based on multidisciplinary discussion by the Liver transplantation team. Patients must demonstrate favorable tumor biology and no evidence of extra hepatic disease. |
|
Recruiting Locations
University of Rochester Medical Center
Rochester, New York 14642
Rochester, New York 14642
More Details
- NCT ID
- NCT05248581
- Status
- Recruiting
- Sponsor
- University of Rochester
Detailed Description
The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation. Our primary outcome of interest was the OS and recurrence-free survival (RFS) of patients who underwent LDLT at our center.